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Particle therapy

Particle therapy

Proton therapy planning: how to minimize LET in organs-at-risk

14 Nov 2022
LET distributions
Treatment plan comparisons CT images overlaid with dose-weighted LET distributions for three planning strategies: the base clinical distribution (left), a three-beam orientation (centre) and an alternate-beam-angle setup (right). The clinical target volume is outlined in red and the brainstem in blue. (Courtesy: CC BY 4.0/J. Appl. Clin. Med. Phys. 10.1002/acm2.13782)
Proton therapy can deliver highly conformal dose distributions to a tumour target while minimizing d

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